20Khz Ultrasonic Cell Pulverizer High Power For Extraction Of
Polygonatum Polysaccharide
Parameter
| Model | SONOL20-300 | SONOL20-500 | SONOL28-300 | SONOL40-100 |
| Frequency | 20±0.5 KHz | 20±0.5 KHz | 28±0.5 KHz | 40±0.5 KHz |
| Power | 300 W | 500 W | 300 W | 100 W |
| Voltage | 220/110V | 220/110V | 220/110V | 220/110V |
| Temperature | 300 ℃ | 300 ℃ | 300 ℃ | 300 ℃ |
| Pressure | 35 MPa | 35 MPa | 35 MPa | 35 MPa |
| Max Capacity | 2 L/Min | 5 L/Min | 1L/Min | 0.5 L/Min |
| Tip Head Material | Titanium Alloy | Titanium Alloy | Titanium Alloy | Titanium Alloy |
Description
The ultrasonic cell pulverizer is based on the cavitation effect of
ultrasonic waves in the liquid. The transducer generates
high-strength shearing force in the liquid at the top of the tool
head through the horn through the electric energy, forming
high-frequency alternating water pressure and expanding the cavity
, The explosion crushes the cells. It can be used to break animal
and plant tissues, cells, bacteria, and spores, and can be used to
emulsify, separate, disperse, homogenize, extract, degas, clean and
accelerate chemical reactions, etc. Ultrasonic cell pulverizers are
widely used in teaching, scientific research, and production in the
fields of biochemistry, microbiology, medicinal chemistry, surface
chemistry, physics, zoology, agronomy, medicine, and pharmacy.
Principle
Ultrasound is an elastic mechanical wave in a material medium. It
is a form of fluctuation, so it can be used to detect the
physiological and pathological information of the human body, as
well as diagnostic ultrasound. At the same time, it is also a form
of energy. When a certain dose of ultrasound is transmitted in the
organism, the interaction between them can cause the function and
structure of the organism to change, that is, the biological effect
of ultrasound.
Ultrasonic cell crusher mainly has thermal effect, cavitation
effect and mechanical effect on cells.
The thermal effect is that when the ultrasound propagates in the
medium, the frictional force hinders the molecular vibration caused
by the ultrasound, which converts part of the energy into local
hyperthermia (42-43℃), because the critical lethal temperature of
normal tissue is 45.7℃, while that of tumor tissue Normal tissues
are highly sensitive, so the metabolism of tumor cells is impaired
at this temperature, and DNA, RNA, and protein synthesis are
affected, thereby killing cancer cells while normal tissues are not
affected.
Cavitation effect is the formation of vacuoles in the organism
under ultrasonic irradiation, and mechanical shearing pressure and
turbulence are generated with the vibration of the vacuoles and
their violent implosion, causing tumor hemorrhage, tissue collapse
and necrosis. In addition, instantaneous high temperature (about
5000°C) and high pressure (up to 500×104Pa) are generated when the
cavitation bubble bursts, which can thermally dissociate water
vapor to produce ·OH radicals and ·H atoms, which are composed of
·OH radicals and ·H Redox reactions caused by atoms can lead to
polymer degradation, enzyme inactivation, lipid peroxidation and
cell killing.
The mechanical effect is the primary effect of ultrasound. The
alternating compression and expansion of the medium particles
during the propagation of ultrasound constitutes a pressure change,
which causes damage to the cell structure. The strength of the
killing effect is closely related to the frequency and intensity of
ultrasound.
Function
Ultrasonic cell pulverizer can be used for scientific research in
medicine. The research in medicine is mainly the extensive use of
the function of crushing. This aspect has extremely high technical
requirements.
Ultrasonic cell crusher can be used to crush animal, plant cells,
bacteria, dental spores or tissues. Disperse rare earth and various
inorganic mineral powders.
Ultrasonic cell crusher is an ideal device to accelerate the
reaction speed of chemistry, biology and physics and accelerate the
degassing of liquids.
Ultrasonic cell pulverizer can prepare latex with a size of nearly
one hundredth of a micron; homogenize the "immiscible" mixture;
polymerize some substances and precipitate others.
Pictures
